Description

Tezacitabine is a synthetic nucleoside analog with significant potential in pharmaceutical research and development. This compound is valued for its role as a cytidine deaminase inhibitor, which is crucial for studying nucleotide metabolism and developing novel therapeutic agents. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors, particularly those focused on oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced investigational drugs.
• Biochemical Research: Used as a potent inhibitor of cytidine deaminase in enzymatic and metabolic pathway studies.
• Oncology Research: Investigated for its potential to modulate nucleotide pools and enhance the efficacy of nucleoside-based chemotherapeutic agents.
• Antiviral Drug Development: Explored in research targeting viruses that are susceptible to modulation of host nucleotide metabolism.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* models to assess pharmacokinetics and mechanism of action.

Basic Information

Product Name	Tezacitabine
CAS No.	171176-43-5
Molecular Formula	C9H12FN3O4
Molecular Weight	245.21 g/mol
Synonyms	4'-Thio-2'-deoxy-2',2'-difluorocytidine; MDL 101,731; 1-(4-Thio-2,2-difluoro-2-deoxy-β-D-erythro-pentofuranosyl)cytosine; 2',2'-Diflu-oro-4'-thiocytidine; Tezacitabin; (-)-Tezacitabine
EINECS	Contact for details

Quality Control

Every batch of Tezacitabine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency of the product meet the exacting requirements of research and development. A Certificate of Analysis (COA) detailing specifications such as assay, purity by HPLC, and identification is available for each lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.