Description

1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphate(Monosodium Salt) is a high-purity, synthetic phospholipid, specifically a phosphatidic acid (PA) derivative, widely used as a critical biochemical reagent and a key intermediate in lipid research and formulation. This compound is essential for studying lipid signaling pathways, membrane biophysics, and for the development of advanced lipid-based delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications ranging from liposome preparation to cell culture media supplementation.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key component for constructing model membranes and drug delivery vehicles, including mRNA vaccines.
• Biochemical & Cell Biology Research: Used as a substrate or signaling molecule in studies of phospholipase D (PLD) activity, membrane fusion, and intracellular signaling cascades.
• Cell Culture & Media Supplementation: Employed as a lipid source in serum-free media formulations to support specialized cell growth.
• Pharmaceutical Excipient: Acts as an emulsifier or stabilizer in complex parenteral formulations and topical products.
• Reference Standard: Serves as a high-purity analytical standard for quality control in lipidomics and pharmaceutical testing.
• Biomimetic Material Synthesis: Used in the creation of synthetic membranes and coatings for biosensors and diagnostic devices.

Basic Information

Product Name	1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphate(Monosodium Salt)
CAS No.	169437-35-8
Molecular Formula	C37H70NaO8P
Molecular Weight	720.91 g/mol
Synonyms	POPA (sodium salt); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate sodium salt; PA(16:0/18:1) sodium salt; Phosphatidic Acid (16:0/18:1) sodium salt; (2R)-2-(Hexadecanoyloxy)-3-[(Z)-octadec-9-enoyloxy]propyl hydrogen phosphate sodium salt; POPA-Na; 1-Palmitoyl-2-oleoyl-phosphatidic acid monosodium salt; Sodium 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphate(Monosodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support research and cGMP applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR & MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (TLC)	Single spot
Solubility	Soluble in chloroform, methanol, ethanol; forms dispersions in water
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.