Description

N(6)-(2-Aminoethyl)Fad CAS NO 167962-39-2 is a chemically modified derivative of flavin adenine dinucleotide (FAD), a critical coenzyme in numerous biological redox reactions. This specialized compound is engineered to introduce a reactive aminoethyl handle, enabling its covalent conjugation to proteins, surfaces, or other molecules for advanced biochemical research and diagnostic applications. It is primarily utilized by researchers and developers in the fields of bioconjugation, enzymology, biosensor development, and pharmaceutical discovery.

Application

• Enzyme Activity Studies & Labeling: Site-specific labeling of flavoproteins to study enzyme mechanisms, dynamics, and interactions.
• Biosensor Fabrication: Immobilization of FAD-dependent enzymes onto electrodes or chips for constructing sensitive electrochemical and optical biosensors.
• Bioconjugation & Probe Development: Serving as a key intermediate for synthesizing fluorescent, affinity, or therapeutic probes targeting flavoenzymes.
• Structural Biology: Aiding in X-ray crystallography and NMR studies by providing a stable, modified cofactor for protein crystallization.
• Drug Discovery Screening: Used in high-throughput assays to identify inhibitors or activators of clinically relevant flavoenzymes.
• Diagnostic Reagent Synthesis: Component in the development of diagnostic kits for monitoring metabolic disorders related to flavoenzyme function.

Basic Information

Product Name	N(6)-(2-Aminoethyl)Fad
CAS No.	167962-39-2
Molecular Formula	C29H39N10O15P2
Molecular Weight	829.64 g/mol
Synonyms	2'-Aminoethyl-FAD; N6-(2-Aminoethyl)flavin adenine dinucleotide; Aminoethyl-FAD; FAD-2'-aminoethyl; Flavin Adenine Dinucleotide, N(6)-(2-aminoethyl)-; 6-(2-Aminoethyl)amino-FAD; AE-FAD; Modified FAD cofactor
EINECS	Contact for details

Quality Control

Our N(6)-(2-Aminoethyl)Fad is produced under stringent quality management protocols. Each batch is characterized and tested to ensure high purity and consistency, suitable for sensitive research applications. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications such as purity (HPLC), identity (UV-Vis, MS), and functional activity. We adhere to ISO 9001 standards to guarantee reliable supply and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (UV-Vis)	Characteristic absorption maxima at ~260 nm & ~450 nm
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% of theoretical activity
Water Content (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.