Description

(+/-)-13-Hydroxy-9Z,11E-Octadecadienoic Acid, Cholesteryl Ester is a specialized conjugated linoleic acid (CLA) derivative, where the hydroxy fatty acid is esterified with cholesterol. This compound is significant as a high-purity biochemical standard and a key synthetic intermediate for research into lipid metabolism, signaling pathways, and the development of analytical methods. It is primarily required by research institutions, pharmaceutical R&D laboratories, and manufacturers of diagnostic reagents focusing on cardiovascular disease, inflammation, and lipidomics.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments like HPLC, GC-MS, and LC-MS in lipid analysis.
• Pharmaceutical R&D: Serves as a critical intermediate in the synthesis of novel drug candidates targeting lipid-related disorders, inflammation, and oxidative stress pathways.
• Diagnostic Reagent Manufacturing: Employed in the production of assay kits and calibrators for the clinical measurement of oxidized lipids and cholesterol esters.
• Lipidomics & Metabolomics: Acts as a standard compound for identifying and quantifying complex lipid species in biological samples for systems biology studies.
• Nutritional Science Research: Investigated for its role and effects as a metabolite of conjugated linoleic acid (CLA) in metabolic studies.
• Cell Signaling Studies: Utilized in vitro to study the biological activity and receptor interactions of oxidized cholesterol esters and hydroxy fatty acids.

Basic Information

Product Name	(+/-)-13-Hydroxy-9Z,11E-Octadecadienoic Acid, Cholesteryl Ester
CAS No.	167354-91-8
Molecular Formula	C45H78O3
Molecular Weight	667.1 g/mol
Synonyms	13-Hydroxy-9Z,11E-octadecadienoic acid cholesteryl ester; 13-HODE cholesteryl ester; Cholesteryl 13-hydroxy-9Z,11E-octadecadienoate; Cholesteryl 13-HODE; 13-Hydroxyoctadecadienoic acid cholesterol ester; CLA derivative cholesterol ester; (9Z,11E,13S)-13-Hydroxyoctadeca-9,11-dienoic acid cholesteryl ester; Oxidized cholesterol ester standard
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of (+/-)-13-Hydroxy-9Z,11E-Octadecadienoic Acid, Cholesteryl Ester is characterized using advanced analytical techniques (NMR, MS, HPLC) to confirm identity and purity, meeting the stringent requirements for research-grade biochemicals. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in chloroform, DMSO; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.