Description

D-Myo-Inositol, 1-(2R)-2,3-Bis(1-Oxohexadecyl)Oxypropyl Hydrogen Phosphate 3,4-Bis(Dihydrogen Phosphate) is a complex, high-purity phospholipid derivative of inositol, specifically designed for advanced biochemical and pharmaceutical research. This compound is critical for studying cell signaling pathways, particularly those involving phosphatidylinositol phosphates (PIPs) which are fundamental to cellular communication, membrane trafficking, and growth regulation. It serves as a key intermediate and reference standard for researchers and manufacturers in lipidomics, drug discovery, and the development of novel therapeutic agents targeting metabolic and neurological disorders.

Application

• Biochemical Research: Essential reference standard and substrate for studying phosphatidylinositol (PI) and phosphoinositide kinases, phosphatases, and phospholipases in cell signaling cascades.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of complex lipid-based drug candidates, including those for cancer, diabetes, and neurological diseases.
• Lipidomics & Metabolomics: Used as a high-purity analytical standard for mass spectrometry and chromatography to identify and quantify inositol phospholipids in biological samples.
• Cell Biology Studies: Applied in research on membrane dynamics, intracellular signaling, and the role of specific phosphoinositides in cellular processes like autophagy and cytoskeletal organization.
• Enzyme Assay Development: Utilized as a specific substrate for screening and characterizing enzymes involved in the phosphoinositide cycle.
• Production of Specialty Lipids: Acts as a building block for the synthesis of other labeled (e.g., fluorescent, radioactive) or modified phosphoinositide derivatives for advanced research applications.

Basic Information

Item	Details
Product Name	D-Myo-Inositol, 1-(2R)-2,3-Bis(1-Oxohexadecyl)Oxypropyl Hydrogen Phosphate 3,4-Bis(Dihydrogen Phosphate)
CAS No.	165883-85-2
Molecular Formula	C41H80O18P3
Molecular Weight	929.99 g/mol
Synonyms	1-(2R)-2,3-Bis(palmitoyloxy)propyl D-myo-inositol 3,4-bis(dihydrogen phosphate) 1-hydrogen phosphate; Phosphatidyl-D-myo-inositol 3,4-bisphosphate (PtdIns(3,4)P2) analog; 1-Palmitoyl-2-palmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate); PtdIns(3,4)P2 (dipalmitoyl); Dipalmitoyl PtdIns(3,4)P2; PI(3,4)P2 (C16:0/C16:0); 1,2-Dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)
EINECS	Contact for details

Quality Control

Our high-purity biochemical grade D-Myo-Inositol derivative is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and mass spectrometry to confirm identity, isomeric purity, and chemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications such as assay purity, impurity profile, and solvent residues. Our quality commitment ensures the consistency and reliability required for sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isomeric Purity	≥ 98% (sn-1,2-dipalmitoyl; D-myo-inositol)
Water Content (KF)	≤ 2.0 %
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.