Description

Depbt CAS NO 165534-43-0 is a specialized peptide coupling reagent widely used in solid-phase peptide synthesis (SPPS) and organic synthesis. Its primary value lies in its efficiency as an activator for carboxylic acids, facilitating the formation of amide bonds with high yields and minimal racemization. This makes it an essential reagent for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing peptide-based therapeutics, APIs, and complex organic molecules.

Application

• Activation agent in solid-phase peptide synthesis (SPPS) for the production of therapeutic peptides.
• Coupling reagent for amide bond formation in organic and medicinal chemistry research.
• Critical component in the synthesis of active pharmaceutical ingredients (APIs) and complex biomolecules.
• Used in combinatorial chemistry libraries for drug discovery and development.
• Facilitates the synthesis of peptide nucleic acids (PNAs) and other peptide conjugates.
• Employed in process development and scale-up manufacturing of peptide drugs.

Basic Information

Product Name	Depbt
CAS No.	165534-43-0
Molecular Formula	C15H21N3O3
Molecular Weight	291.35 g/mol
Synonyms	3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one; DEPBT; 1,2,3-Benzotriazin-4(3H)-one, 3-[(diethoxyphosphinyl)oxy]-; 3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4-one; Benzotriazinone DEPBT; Peptide Coupling Reagent DEPBT
EINECS	Contact for details

Quality Control

Our Depbt is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and cGMP manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.