Description

Suc-Gly-Phe-Gly-Pna CAS NO 165174-57-2 is a synthetic peptide substrate designed for biochemical research and pharmaceutical development. This compound is critical for studying enzyme kinetics and activity, particularly for proteases and peptidases. It is an essential tool for researchers in pharmaceutical R&D, diagnostic assay development, and academic biochemistry laboratories requiring high-purity, well-characterized substrates.

Application

• Enzyme Substrate for Protease Research: Used as a specific chromogenic or fluorogenic substrate to measure the activity and kinetics of various proteolytic enzymes.
• Pharmaceutical Screening Assays: Employed in high-throughput screening (HTS) platforms to identify and characterize potential protease inhibitors for drug discovery.
• Biochemical Pathway Analysis: Facilitates the study of enzymatic pathways and mechanisms in cellular processes and disease models.
• Diagnostic Reagent Component: Serves as a key component in the development of in-vitro diagnostic (IVD) kits for detecting specific enzyme activities.
• Quality Control in Biologics: Used to monitor and ensure the consistency and activity of enzyme-based biopharmaceutical products during manufacturing.

Basic Information

Product Name	Suc-Gly-Phe-Gly-Pna
CAS No.	165174-57-2
Molecular Formula	C26H30N6O8
Molecular Weight	554.55 g/mol
Synonyms	N-Succinyl-Glycyl-Phenylalanyl-Glycyl-4-Nitroanilide; Suc-Gly-Phe-Gly-pNA; N-Succinyl-Gly-Phe-Gly-p-Nitroanilide; Substrate for Chymotrypsin; Suc-Gly-Phe-Gly-4-NA; SGFG-pNA; Protease Substrate SGFG-pNA; N-Succinyl-Glycine-Phenylalanine-Glycine-4-Nitroanilide
EINECS	Contact for details

Quality Control

Our Suc-Gly-Phe-Gly-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional activity assays. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water
Functional Activity	Conforms to expected enzymatic cleavage profile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.