Description

Kukoamine B CAS NO 164991-67-7 is a naturally occurring spermine alkaloid, a polyamine derivative with a unique structural framework. This compound is of significant interest due to its potent biological activities, particularly its role as a high-affinity antagonist for specific receptors involved in inflammatory and neurological pathways. It is primarily utilized by researchers and developers in the pharmaceutical and life science sectors for drug discovery, mechanism-of-action studies, and as a key reference standard in analytical chemistry.

Application

• Pharmaceutical Research & Development: Serves as a critical lead compound or reference standard in the discovery of novel therapeutics targeting inflammation and neurological disorders.
• Biochemical Research: Used as a selective molecular probe to study polyamine transport systems and receptor-ligand interactions in cellular models.
• Analytical Reference Standard: Essential for the qualitative and quantitative analysis (HPLC, LC-MS) of Kukoamine B in complex matrices for quality control and method validation.
• Natural Product Chemistry: A subject of study for isolation, synthesis, and structure-activity relationship (SAR) analysis of bioactive alkaloids.
• Preclinical Studies: Investigated for its potential pharmacological effects in animal models related to its known biological targets.

Basic Information

Product Name	Kukoamine B
CAS No.	164991-67-7
Molecular Formula	C28H42N6O6
Molecular Weight	558.67 g/mol
Synonyms	N1,N14-Bis(dihydrocaffeoyl)spermine; Lyciumamide B; Kukoamine B (Lycium chinense); (1E,6E)-1,7-Bis(3,4-dihydroxyphenyl)-N1,N14-bis(3-(3,4-dihydroxyphenyl)acryloyl)-1,6-heptadiene-3,5,11,13-tetraamine; Kukoamine B Alkaloid
EINECS	Contact for details

Quality Control

Our Kukoamine B is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for reference materials, and custom purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccation and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95% (Standard Grade)
Purity (HPLC)	≥98% (High Purity Grade)
Water Content (KF)	≤5.0%
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.