Description

Rac-2-Methoxy-3-Hexadecanamido-1-Propyl Phosphocholine is a synthetic phospholipid derivative, a key intermediate in advanced lipid research and development. This compound is valued for its role in modulating membrane properties and serving as a precursor for novel liposomal and lipid nanoparticle formulations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for drug delivery systems, biomimetic membrane studies, and specialty surfactant applications.

Application

• Lipid Nanoparticle (LNP) Formulation: A critical building block for constructing ionizable or cationic lipids used in mRNA and siRNA delivery systems.
• Liposomal Drug Delivery: Serves as a functionalized phospholipid component to create targeted or stealth liposomes for encapsulating therapeutic agents.
• Biomimetic Membrane Research: Used in model membrane systems (e.g., vesicles, supported lipid bilayers) to study membrane fluidity, protein-lipid interactions, and signaling.
• Pharmaceutical Intermediates: Acts as a key synthetic precursor for the production of more complex, pharmacologically active phospholipids.
• Specialty Surfactants & Amphiphiles: Employed in the development of high-performance detergents, emulsifiers, and dispersants for niche industrial applications.
• Diagnostic Reagent Development: Utilized in formulating components for diagnostic assays and imaging contrast agents.

Basic Information

Product Name	Rac-2-Methoxy-3-Hexadecanamido-1-Propyl Phosphocholine
CAS No.	163751-35-7
Molecular Formula	C₂₅H₅₃N₂O₆P
Molecular Weight	508.67 g/mol
Synonyms	2-Methoxy-3-(palmitamido)propyl 2-(trimethylammonio)ethyl phosphate; 1-Hexadecanamido-2-methoxy-3-phosphocholinopropane (racemic); Rac-PC(16:0/OMe); 3-Hexadecanamido-2-methoxypropyl phosphocholine; Lyso-PAF C-16 analogue; 1-O-Methyl-2-palmitamido-sn-glycero-3-phosphocholine (racemic); Glycerophosphocholine derivative, 2-methoxy-3-palmitamido; Phosphatidylcholine analogue, methoxy-substituted
EINECS	Contact for details

Quality Control

Every batch of Rac-2-Methoxy-3-Hexadecanamido-1-Propyl Phosphocholine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and cGMP-grade material production. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), impurity profile, and other critical specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store the product under an inert atmosphere (argon or nitrogen) at -20°C or below for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single major spot
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.