Description

Guanosine-9-17N, n-(2-Methyl-1-Oxopropyl)-, 2',3'-Diacetate is a specifically modified nucleoside derivative, isotopically labeled with nitrogen-17 at the 9-position. This compound is of significant value as a high-purity biochemical building block and a stable isotope-labeled standard for advanced research. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in metabolic pathway studies, analytical method development, and the synthesis of novel bioactive molecules.

Application

• Stable Isotope-Labeled Internal Standard for the precise quantification of nucleosides and related metabolites in complex biological matrices using LC-MS/MS and GC-MS.
• Biochemical Research Reagent for studying nucleoside metabolism, enzyme kinetics, and transport mechanisms in cellular systems.
• Pharmaceutical Intermediate in the research and development of novel antiviral or anticancer nucleoside analog therapeutics.
• Metabolic Pathway Tracing in isotope labeling experiments to investigate the biosynthesis and catabolism of purines.
• Analytical Reference Standard for method validation, calibration, and quality control in analytical laboratories.
• Precursor for Chemical Synthesis of more complex labeled compounds for use in spectroscopy (NMR) and mechanistic studies.

Basic Information

Item	Details
Product Name	Guanosine-9-17N, n-(2-Methyl-1-Oxopropyl)-, 2',3'-Diacetate
CAS No.	163586-86-5
Molecular Formula	C17H2317N5O8
Molecular Weight	Contact for details
Synonyms	9-(2-Methyl-1-oxopropyl)guanine-9-17N 2',3'-diacetate; N2-(2-Methylpropionyl)-9-(β-D-ribofuranosyl)guanine-9-17N 2',3'-diacetate; Guanosine, N-(2-methyl-1-oxopropyl)-, 2',3'-diacetate, 9-17N; Isotopically labeled N2-isobutyryl-2',3'-O-diacetylguanosine-9-17N; [9-17N]-N2-Isobutyryl-2',3'-di-O-acetylguanosine
EINECS	Contact for details

Quality Control

Our Guanosine-9-17N, n-(2-Methyl-1-Oxopropyl)-, 2',3'-Diacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and isotopic enrichment verification. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Enrichment (17N)	≥ 95 atom %
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.