Description

9-Cyano-N,N,N'-Triethylpyronine-N'-Caproic Acid N 4-(Maleimidoethyl)Piperazide Chloride is a specialized heterocyclic organic compound designed for advanced bioconjugation and labeling applications. This molecule matters for its dual functionality, combining a reactive maleimide group for selective thiol coupling with a cyanine-like pyronine fluorophore structure, enabling the creation of stable, fluorescent probes. It is primarily needed by researchers and manufacturers in the life sciences sector, particularly for developing diagnostic assays, targeted drug delivery systems, and high-sensitivity bioimaging reagents.

Application

• Fluorescent Probe Synthesis: Acts as a key intermediate for creating site-specific fluorescent labels for proteins, antibodies, and peptides.
• Bioconjugation Reagent: Utilized for covalently attaching reporter molecules or therapeutic payloads to biomolecules via its maleimide-thiol chemistry.
• Diagnostic Assay Development: Used in the manufacturing of components for ELISA, lateral flow assays, and other in-vitro diagnostic (IVD) kits.
• Bioimaging Agent Precursor: Serves as a building block for near-infrared (NIR) or visible-light fluorophores used in cellular and in vivo imaging.
• Pharmaceutical Research: Employed in the R&D of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Polymer Functionalization: Can be used to introduce reactive sites and fluorescent properties onto polymers and nanoparticles.

Basic Information

Product Name	9-Cyano-N,N,N'-Triethylpyronine-N'-Caproic Acid N 4-(Maleimidoethyl)Piperazide Chloride
CAS No.	163032-73-3
Molecular Formula	C₃₆H₅₀ClN₅O₄
Molecular Weight	656.27 g/mol
Synonyms	9-Cyano-N,N,N'-triethylpyronine-N'-caproic acid N-4-(maleimidoethyl)piperazide chloride; Pyronine maleimide derivative; Cyanine-piperazine-maleimide conjugate; N-(6-(4-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)piperazin-1-yl)-6-oxohexyl)-9-cyano-2,7-bis(ethylamino)-N,N-diethyl-3H-xanthen-3-iminium chloride; Bioconjugation linker-fluorophore hybrid; Thiol-reactive pyronine dye.
EINECS	Contact for details

Quality Control

Our production of 9-Cyano-N,N,N'-Triethylpyronine-N'-Caproic Acid N 4-(Maleimidoethyl)Piperazide Chloride adheres to stringent quality protocols suitable for research and diagnostic applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and functional performance. Certificates of Analysis (COA) detailing specifications such as HPLC purity, functional group reactivity, and spectroscopic properties are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant in a freezer dedicated for chemicals. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.