Description

n-Biotinylaminoethyl Methanethiosulfonate is a specialized bioconjugation reagent designed for the site-specific labeling of proteins and other biomolecules. This compound matters for researchers and manufacturers requiring high-precision covalent attachment of biotin tags to cysteine residues, enabling downstream detection, purification, and analysis. It is primarily needed by biotechnology, pharmaceutical, and diagnostic companies engaged in assay development, proteomics research, and the production of biotinylated therapeutic agents.

Application

• Site-specific biotinylation of cysteine residues in proteins and peptides for structural studies.
• Preparation of biotinylated probes for use in ELISA, Western blotting, and other immunoassay platforms.
• Conjugation reagent in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs).
• Tool compound in proteomics for affinity purification and pull-down assays to study protein-protein interactions.
• Labeling agent for surface plasmon resonance (SPR) and other biosensor chip functionalization.
• Critical reagent in the synthesis of diagnostic kits and molecular imaging agents.

Basic Information

Product Name	n-Biotinylaminoethyl Methanethiosulfonate
CAS No.	162758-04-5
Molecular Formula	C13H21N3O4S2
Molecular Weight	347.45 g/mol
Synonyms	Biotin-PEO2-MTS; Biotin-PEG2-Methanethiosulfonate; 2-((Biotinoyl)amino)ethyl methanethiosulfonate; Biotinamidoethyl Methanethiosulfonate; Biotin-HPDP; N-Biotinyl-2-aminoethyl Methanethiosulfonate; Biotinylaminoethyl MTS; MTSEA-Biotin
EINECS	Contact for details

Quality Control

Our n-Biotinylaminoethyl Methanethiosulfonate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and bioconjugation applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and ensure long-term stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.