Description

n-(2-Hydroxyethyl)Piperazine-N'-(4-Butanesulfonic Acid) is a high-purity biochemical buffer agent, also known as HEPBS, valued for its excellent buffering capacity in the physiological pH range. This compound is critical for applications requiring precise pH control and stability in sensitive biological and chemical systems. It is primarily needed by researchers and manufacturers in the life sciences, pharmaceutical development, and specialty chemical synthesis sectors.

Application

• As a biological buffer in cell culture media, protein purification, and enzymatic assays.
• In the formulation of diagnostic reagents and kits requiring stable pH environments.
• As a key component in pharmaceutical intermediates and active pharmaceutical ingredient (API) synthesis.
• For biochemical research, including electrophoresis, chromatography, and molecular biology techniques.
• In the preparation of cosmetic and personal care formulations where pH stability is essential.
• As a specialized additive in industrial processes involving sensitive catalysts or reactions.

Basic Information

Product Name	n-(2-Hydroxyethyl)Piperazine-N'-(4-Butanesulfonic Acid)
CAS No.	161308-36-7
Molecular Formula	C10H22N2O4S
Molecular Weight	266.36 g/mol
Synonyms	HEPBS; N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid); 1-(2-Hydroxyethyl)piperazine-1,4-dibutanesulfonic acid; 2-[4-(4-Sulfobutyl)piperazin-1-yl]ethanol; Piperazine-1,4-dibutanesulfonic acid, 1-(2-hydroxyethyl)-; EPPS derivative; Good's buffer HEPBS; (2-Hydroxyethyl)piperazinebutanesulfonic acid
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxyethyl)Piperazine-N'-(4-Butanesulfonic Acid) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (1% Solution)	7.0 - 8.0
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.