Description

Docosahexaenoic Acid n-Succinimide is a high-purity, chemically modified derivative of the essential ω-3 fatty acid DHA. This compound is specifically engineered to enhance the bioavailability and stability of DHA for advanced pharmaceutical and nutraceutical applications. It serves as a critical intermediate for the synthesis of targeted lipid conjugates, primarily utilized by research institutions and manufacturers in the pharmaceutical, dietary supplement, and advanced biomedical materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing targeted prodrugs and bioactive conjugates to improve drug delivery and efficacy.
• Nutraceutical Enhancement: Used in the development of advanced dietary supplements with improved DHA absorption and metabolic stability.
• Biomedical Research: Essential reagent in lipidomics research, cell signaling studies, and the development of novel lipid-based therapeutic agents.
• Cosmetic Actives: Incorporated into high-end skincare formulations for its potential anti-inflammatory and skin-barrier repairing properties.
• Bioconjugation: Serves as a linker molecule for attaching DHA to peptides, proteins, or other drug molecules to create new chemical entities (NCEs).

Basic Information

Product Name	Docosahexaenoic Acid n-Succinimide
CAS No.	160801-26-3
Molecular Formula	C26H37NO4
Molecular Weight	427.58 g/mol
Synonyms	DHA-NHS; DHA N-Hydroxysuccinimide Ester; Docosahexaenoic Acid N-Hydroxysuccinimide Ester; 4,7,10,13,16,19-Docosahexaenoic Acid N-Succinimidyl Ester; N-Succinimidyl Docosahexaenoate; (4Z,7Z,10Z,13Z,16Z,19Z)-N-Hydroxysuccinimidyl Docosa-4,7,10,13,16,19-hexaenoate; ω-3 DHA NHS Ester
EINECS	Contact for details

Quality Control

Our Docosahexaenoic Acid n-Succinimide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical-grade intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between -20°C to -10°C under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to pale yellow solid or oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.