Description

Oxycodone-D3 CAS NO 160227-46-3 is a deuterium-labeled analog of the potent semi-synthetic opioid analgesic, oxycodone. This stable isotope-labeled compound is an essential reference standard and internal standard for precise analytical quantification in research and forensic toxicology. It is primarily utilized by pharmaceutical R&D laboratories, forensic science institutions, and contract research organizations (CROs) for method development and validation.

Application

• Analytical Reference Standard: Serves as a certified reference material (CRM) for the accurate identification and quantification of oxycodone in complex biological matrices using LC-MS/MS and GC-MS.
• Pharmacokinetic and Metabolic Studies: Used as an internal standard in mass spectrometry to study the absorption, distribution, metabolism, and excretion (ADME) of oxycodone, ensuring high data accuracy.
• Forensic Toxicology and Drug Testing: Critical for confirming the presence of oxycodone in urine, blood, or hair samples with high specificity, supporting legal and workplace testing protocols.
• Pharmaceutical Quality Control: Employed in the assay and impurity profiling of oxycodone active pharmaceutical ingredients (APIs) and finished dosage forms to meet regulatory requirements.
• Clinical Research: Facilitates therapeutic drug monitoring (TDM) and bioequivalence studies for oxycodone-based medications.

Basic Information

Item	Detail
Product Name	Oxycodone-D3
CAS No.	160227-46-3
Molecular Formula	C18H18D3NO4
Molecular Weight	Contact for details
Synonyms	14-Hydroxydihydrocodeinone-D3; Dihydrohydroxycodeinone-D3; Oxycodone-d3 (methyl-d3); 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one-d3; Oxycodone (methyl-d3); Oxycodone-D3 Internal Standard; Deuterated Oxycodone
EINECS	Contact for details

Quality Control

Our Oxycodone-D3 is manufactured and controlled to meet the exacting standards required for analytical and research applications. Each batch undergoes comprehensive testing, including identity confirmation by NMR and mass spectrometry, chemical and isotopic purity determination by HPLC and LC-MS, and verification of residual solvents. A comprehensive Certificate of Analysis (COA) detailing all test results, including isotopic enrichment, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (LC-MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.