Description

α-D-Glucopyranoside, 2,3-Bis((1-Oxohexadecyl)Oxy)Propyl, 6-(2-(Tri Methylammonio)Ethyl Hydrogenphosphate), Inner Salt, (S)- is a sophisticated synthetic phospholipid derivative, designed for advanced formulation and research applications. This compound is valued for its unique amphiphilic structure, which combines a sugar-based head group with long-chain fatty acid esters and a zwitterionic phosphocholine moiety, enabling precise control over surface and membrane interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing targeted delivery systems and biomimetic interfaces.

Application

• Pharmaceutical Excipient: As a functional lipid component in the formulation of liposomes, lipid nanoparticles (LNPs), and other advanced drug delivery systems for enhanced stability and targeted release.
• Biomimetic Membrane Research: For constructing model cell membranes and lipid bilayers to study protein-lipid interactions, membrane permeability, and cellular signaling processes.
• Cosmetic & Dermal Formulations: As a high-performance emulsifier and skin-conditioning agent in premium cosmetic products, improving texture and active ingredient penetration.
• Diagnostic Reagents: In the development of diagnostic kits and assays where stable, functionalized lipid layers are required for sensor surfaces or biomarker capture.
• Bioconjugation & Linker Chemistry: Serving as a versatile scaffold for attaching targeting ligands, dyes, or other functional molecules due to its reactive groups.
• Material Science: For surface modification and creating self-assembled monolayers (SAMs) to control wettability, reduce friction, or prevent biofouling on medical devices.

Basic Information

Product Name	α-D-Glucopyranoside, 2,3-Bis((1-Oxohexadecyl)Oxy)Propyl, 6-(2-(Tri Methylammonio)Ethyl Hydrogenphosphate), Inner Salt, (S)-
CAS No.	158227-74-8
Molecular Formula	C46H90NO13P
Molecular Weight	896.19 g/mol
Synonyms	(S)-6-O-[2-(Trimethylammonio)ethyl]-2,3-di-O-palmitoyl-α-D-glucopyranosyl hydrogen phosphate; 2,3-Di-O-palmitoyl-α-D-glucopyranosyl-6-O-[2-(trimethylammonio)ethyl] hydrogen phosphate; α-D-Glucopyranoside, 2,3-bis((1-oxohexadecyl)oxy)propyl 6-(2-(trimethylammonio)ethyl hydrogen phosphate), inner salt; Phospholipid GLU-PC(16:0); Synthetic glycolipid; Zwitterionic glycosyl phospholipid; Glycolipid-based phosphocholine derivative
EINECS	Contact for details

Quality Control

Our production of this high-purity synthetic lipid adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. We support compliance with cGMP guidelines where required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For short-term use, store in a desiccator at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.