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o-Allyl-n-Benzylcinchondinium Bromide CAS NO 158195-40-5
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CAS No.:158195-40-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
o-Allyl-n-Benzylcinchondinium Bromide is a high-purity, organocatalytic phase-transfer catalyst derived from the cinchona alkaloid family. This compound matters for its critical role in facilitating highly enantioselective chemical transformations, particularly in asymmetric synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of chiral intermediates and active ingredients.
Application
- As a phase-transfer catalyst (PTC) in asymmetric alkylation and conjugate addition reactions.
- Enabling enantioselective synthesis of non-natural amino acids and other chiral building blocks for pharmaceutical APIs.
- Catalyzing stereoselective glycosylation reactions in carbohydrate chemistry.
- Use in the development of novel chiral ligands and catalyst systems.
- Facilitating scale-up processes in fine chemical and agrochemical manufacturing.
- Research and development of new asymmetric catalytic methodologies in academic and industrial laboratories.
Basic Information
| Product Name | o-Allyl-n-Benzylcinchondinium Bromide |
| CAS No. | 158195-40-5 |
| Molecular Formula | C₂₉H₃₅BrN₂O |
| Molecular Weight | 495.51 g/mol |
| Synonyms | O-Allyl-N-benzylcinchondinium Bromide; (8α,9R)-N-Allyl-O-benzylcinchondinium Bromide; 1-Benzyl-9-allylcinchondinium Bromide; Cinchondinium Bromide, N-Allyl-O-benzyl-; Cinchona Alkaloid Phase-Transfer Catalyst; Asymmetric Phase Transfer Catalyst; PTC Catalyst |
| EINECS | Contact for details |
Quality Control
Our o-Allyl-n-Benzylcinchondinium Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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