Description

1-o-(5'-Carboxypentyl)Glycero-3-Phosphothreonine is a high-purity, synthetic phospholipid derivative, a key intermediate in advanced biochemical research and pharmaceutical development. This compound is critical for the synthesis of complex lipid conjugates and for studying membrane-protein interactions. It is primarily utilized by researchers and manufacturers in the fields of lipidomics, drug delivery systems (liposomes), and diagnostic assay development.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel phospholipid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Liposome & Nanoparticle Formulation: Used to create functionalized lipid bilayers for targeted drug delivery and vaccine adjuvants.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies, signal transduction research, and lipid metabolism pathways.
• Diagnostic Reagents: Employed in the development of sensitive immunoassays and biosensors where membrane anchoring is required.
• Proteoliposome Preparation: Facilitates the reconstitution of membrane proteins for structural and functional analysis.
• Surface Chemistry & Bioconjugation: The carboxy group allows for covalent attachment to surfaces, polymers, or other biomolecules.

Basic Information

Product Name	1-o-(5'-Carboxypentyl)Glycero-3-Phosphothreonine
CAS No.	158059-97-3
Molecular Formula	C12H24NO10P
Molecular Weight	373.30 g/mol
Synonyms	1-O-(6-Carboxyhexyl)-2-O-acyl-sn-glycero-3-phosphothreonine; 1-(5'-Carboxypentyl)-2-acyl-glycero-3-phosphothreonine; Glycerophosphothreonine derivative; Phosphatidylthreonine analog; 1-O-(5-Carboxypentyl)-2-acyl-sn-glycero-3-phosphothreonine; sn-Glycero-3-phosphothreonine, 1-(5-carboxypentyl) derivative; Lipid-PThr conjugate; 158059-97-3
EINECS	Contact for details

Quality Control

Our 1-o-(5'-Carboxypentyl)Glycero-3-Phosphothreonine is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (argon or nitrogen). Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.