Description

1-(Saligenin Cyclic Phospho)-9-Biotinyldiaminononane is a sophisticated bifunctional chemical reagent designed for advanced bioconjugation and molecular labeling applications. Its core value lies in combining the high-affinity biotin-binding capability with a reactive phosphoester group, enabling stable and specific attachment to target molecules. This compound is essential for researchers and manufacturers in the fields of diagnostic assay development, proteomics, and targeted drug delivery systems, where precise and robust molecular linkages are critical.

Application

• Diagnostic Reagent Synthesis: Key intermediate for labeling antibodies, antigens, or oligonucleotides in ELISA, lateral flow assays, and other immunoassays.
• Affinity Chromatography Ligand: Used to functionalize solid supports (e.g., agarose beads) for the purification of biotin-binding proteins like streptavidin or avidin.
• Proteomics & Biomarker Research: Enables site-specific biotinylation of proteins or peptides for pull-down assays, mass spectrometry analysis, and protein interaction studies.
• Targeted Drug Conjugates: Serves as a linker in the development of biotin-drug conjugates for receptor-mediated delivery, leveraging the biotin-streptavidin interaction.
• Biosensor Development: Facilitates the immobilization of biomolecules onto sensor surfaces to enhance specificity and signal detection.
• Cell Surface Labeling: Used for tagging specific cell membrane receptors or other surface proteins for imaging or sorting applications.
• Nanoparticle Functionalization: Aids in attaching targeting ligands to nanoparticles for diagnostic or therapeutic purposes.

Basic Information

Product Name	1-(Saligenin Cyclic Phospho)-9-Biotinyldiaminononane
CAS No.	158040-84-7
Molecular Formula	C28H46N5O6PS
Molecular Weight	611.73 g/mol
Synonyms	9-Biotinyldiaminononane Saligenin Cyclic Phospho Ester; Biotinylated Phosphoramidite Reagent; Biotin-LC-Phosphoramidite; N-Biotinyl-1,9-diaminononane Saligenin Cyclic Phosphite; Biotin-PEG-Phosphoramidite (long-chain); Biotin Labeling Reagent; Biotin Phosphoramidite Derivative; 1,9-Diaminononane, N-biotinyl-, cyclic phosphite with saligenin
EINECS	Contact for details

Quality Control

Our production of 1-(Saligenin Cyclic Phospho)-9-Biotinyldiaminononane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive research and diagnostic applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The compound is moisture-sensitive and should be handled under anhydrous conditions when possible. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.