Description

2-Chloro-4-Nitrophenyl-α-L-Fucopyranoside is a specialized chromogenic substrate designed for enzymatic assays. This compound matters for its high specificity in detecting and quantifying the activity of α-L-fucosidase enzymes, a critical biomarker in various biochemical and diagnostic applications. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in lysosomal storage disorder research, cancer biomarker studies, and high-throughput screening.

Application

• Enzymatic Substrate for α-L-Fucosidase: Primary chromogenic substrate used in clinical and research laboratories to measure α-L-fucosidase activity.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits for fucosidosis and other lysosomal storage disorders.
• Biochemical Research: Used in enzyme kinetics studies, inhibitor screening, and characterization of fucosidase enzymes from various biological sources.
• Cancer Biomarker Studies: Employed in assays to investigate altered fucosylation patterns associated with cancer progression and metastasis.
• Quality Control in Biopharma: Used to monitor glycosidase activity during the production and purification of recombinant glycoprotein therapeutics.
• Microbiology Applications: Applied in bacterial identification schemes that rely on specific glycosidase profiles.

Basic Information

Product Name	2-Chloro-4-Nitrophenyl-α-L-Fucopyranoside
CAS No.	157843-41-9
Molecular Formula	C12H14ClNO8
Molecular Weight	335.69 g/mol
Synonyms	4-Nitrophenyl 2-chloro-4-nitrophenyl α-L-fucopyranoside; 2-Chloro-4-nitrophenyl α-L-fucopyranoside; CNP-α-L-Fucopyranoside; α-L-Fucosidase Substrate; p-Nitrophenyl 2-chloro-4-nitrophenyl α-L-fucopyranoside; 2-Chloro-4-nitrophenyl-α-L-fucoside; Chromogenic Fucosidase Substrate
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Nitrophenyl-α-L-Fucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive assays. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.