Description

S-(N,n-Diethylcarbamoyl)Glutathione is a chemically modified derivative of the essential tripeptide glutathione, where a diethylcarbamoyl group is attached to the sulfur atom. This modification enhances its stability and alters its reactivity profile, making it a valuable biochemical tool and a potential precursor in pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying glutathione metabolism, enzyme inhibition, and as a building block for more complex bioactive molecules. Its specific structure offers unique properties for probing biochemical pathways and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a stable, modified substrate or inhibitor in enzymatic studies related to glutathione S-transferases (GSTs) and other redox enzymes.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor or building block in the development of novel drug candidates targeting oxidative stress and detoxification pathways.
• Metabolic Pathway Analysis: Employed in vitro and in cell culture studies to investigate the role of glutathione conjugation in cellular protection and metabolism.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical and research laboratories.
• Prodrug Development: Explored for creating prodrug forms designed to enhance delivery and bioavailability of therapeutic agents.

Basic Information

Product Name	S-(N,n-Diethylcarbamoyl)Glutathione
CAS No.	157723-51-8
Molecular Formula	C15H27N4O7S
Molecular Weight	407.46 g/mol
Synonyms	S-(Diethylcarbamoyl)glutathione; Glutathione S-(N,N-diethylcarbamate); N-(N-L-γ-Glutamyl-L-cysteinyl)glycine S-(N,N-diethylcarbamate); L-Glutathione, S-(N,N-diethylcarbamate); GSH Diethylcarbamate; S-Carbamoylglutathione (Diethyl derivative); S-(Diethylcarbamothioyl)glutathione
EINECS	Contact for details

Quality Control

Every batch of S-(N,n-Diethylcarbamoyl)Glutathione is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for research and development applications. A detailed Certificate of Analysis (COA) specifying results for appearance, identification, assay, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.