Description

Cytochrome P450 4D2 is a highly specialized, membrane-bound hemoprotein belonging to the cytochrome P450 superfamily of enzymes. This enzyme plays a critical role in the oxidative metabolism of a diverse array of endogenous compounds and xenobiotics, making it an essential tool for pharmacological and toxicological research. It is particularly valuable for researchers in the pharmaceutical, biotechnology, and academic sectors studying drug metabolism, enzyme kinetics, and metabolic pathway analysis. The compound is supplied as a high-purity, research-grade material to ensure reliable and reproducible experimental results.

Application

• Drug Metabolism Studies: Used as a key reagent for in vitro assays to investigate the metabolic pathways and clearance rates of new chemical entities (NCEs) and pharmaceutical candidates.
• Enzyme Kinetics & Inhibition Screening: Essential for determining kinetic parameters (Km, Vmax) and for high-throughput screening of potential enzyme inhibitors or inducers in drug discovery pipelines.
• Metabolite Identification: Facilitates the structural identification and characterization of drug metabolites in preclinical development stages.
• Biochemical Research: Serves as a standard or control in studies focusing on the structure, function, and regulation of cytochrome P450 enzymes.
• Toxicology Assessment: Employed to evaluate the bioactivation of protoxins and the formation of reactive metabolites that may cause organ toxicity.
• Personalized Medicine Research: Supports investigations into pharmacogenomics and inter-individual variability in drug response linked to specific CYP isoforms.

Basic Information

Product Name	Cytochrome P450 4D2
CAS No.	157574-86-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP4D2; Cytochrome P450 4D2; CYP4D2 Enzyme; Cytochrome P450 Family 4 Subfamily D Member 2; P450 4D2; Hemoprotein 4D2; Microsomal Monooxygenase 4D2
EINECS	Contact for details

Quality Control

Our Cytochrome P450 4D2 is produced and controlled under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and functional activity. Key parameters assessed include specific content (nmol P450/mg protein), spectral purity, and enzymatic activity using standard probe substrates. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all test results against established specifications to guarantee batch-to-batch consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -70°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. For short-term use, store at 2-8°C for up to one week. Always handle on ice or in a cold environment during preparation.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (Spectral)	Complies (Characteristic Soret peak ~450 nm)
Specific Content	≥ 5 nmol P450/mg protein
Purity (SDS-PAGE)	≥ 90%
Activity (Probe Substrate)	Contact for details
Protein Concentration	Provided on COA
Buffer Composition	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.