Description

D-Myo-Inositol-1,4,6-Triphosphate (Sodium Salt) is a high-purity, biologically active inositol phosphate derivative essential for intracellular signaling research. This compound serves as a critical second messenger analog, specifically modulating calcium ion release from endoplasmic reticulum stores. It is primarily utilized by researchers in biochemistry, pharmacology, and cell biology for studying phosphoinositide signaling pathways, receptor activation mechanisms, and cellular communication processes.

Application

• Biochemical Research: A key tool for investigating the phosphoinositide signaling cascade and inositol trisphosphate (IP3) receptor function in vitro.
• Cell Signaling Studies: Used to stimulate calcium mobilization in cell-based assays to study downstream physiological responses.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) to identify and characterize novel agonists or antagonists of the IP3 receptor for therapeutic targeting.
• Enzymology: Serves as a specific substrate or modulator for studying the activity of kinases, phosphatases, and phospholipases involved in inositol metabolism.
• Neuroscience Research: Applied in studies of neuronal signal transduction, synaptic plasticity, and the role of calcium in neurotransmitter release.
• Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical equipment and validation of assay methods in quality control laboratories.

Basic Information

Product Name	D-Myo-Inositol-1,4,6-Triphosphate (Sodium Salt)
CAS No.	157380-18-2
Molecular Formula	C6H12Na3O15P3 • xH2O
Molecular Weight	Anhydrous: 504.04 g/mol
Synonyms	Ins(1,4,6)P3 Sodium Salt; D-myo-Inositol 1,4,6-trisphosphate trisodium salt; Inositol 1,4,6-trisphosphate; IP3 (1,4,6); 1,4,6-IP3; myo-Inositol 1,4,6-trisphosphoric acid trisodium salt
EINECS	Contact for details

Quality Control

Our D-Myo-Inositol-1,4,6-Triphosphate (Sodium Salt) is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 98% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.