Description

Dihydronorcodeine 6-Glucuronide is a high-purity reference standard and key metabolite of opioid compounds. This compound is critical for analytical research and pharmaceutical development, providing a definitive benchmark for identification and quantification. It is primarily required by pharmaceutical R&D laboratories, forensic toxicology units, and clinical research organizations for method validation, metabolic pathway studies, and bioanalytical applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quantitative analysis of opioid metabolites in drug development and bioequivalence studies.
• Forensic Toxicology: Essential for the accurate identification and confirmation of dihydronorcodeine metabolites in biological samples for legal and workplace testing.
• Clinical Research: Employed in pharmacokinetic and metabolic studies to understand the disposition and clearance of opioid-based medications.
• Biomarker Research: Serves as a precise biomarker in studies investigating individual metabolic variations and enzyme activity related to glucuronidation pathways.
• Quality Control (QC) Testing: Utilized by pharmaceutical manufacturers for in-process testing and final product release of related opioid analgesics.
• Academic Research: Applied in university and institutional labs for fundamental research on drug metabolism, conjugation reactions, and analytical method development.

Basic Information

Product Name	Dihydronorcodeine 6-Glucuronide
CAS No.	157287-30-4
Molecular Formula	C24H29NO9
Molecular Weight	475.49 g/mol
Synonyms	Dihydronorcodeine 6-O-β-D-Glucuronide; Norcodeine-6-glucuronide, dihydro-; 6-Glucuronide of Dihydronorcodeine; 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6α-ol 6-Glucuronide; Dihydro-7,8-dihydronorcodeine 6-glucuronide; Dihydronorcodeine Glucuronide; Dihydro-7,8-norcodeine 6-glucuronide
EINECS	Contact for details

Quality Control

Our Dihydronorcodeine 6-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.