Description

Arg-Pro-p-Nitroanilide Acetate Salt is a specialized synthetic peptide derivative, primarily utilized as a chromogenic substrate for enzymatic assays. This compound is critical for researchers and manufacturers requiring precise, high-quality biochemical tools for diagnostic and proteomic applications. It is essential for pharmaceutical R&D, clinical diagnostics, and academic research focused on enzyme kinetics and inhibitor screening.

Application

• Enzymatic Substrate: Primarily used as a chromogenic substrate for the assay of proteolytic enzymes, including trypsin, thrombin, and other serine proteases.
• Pharmaceutical Research: Employed in high-throughput screening (HTS) for the discovery and development of novel protease inhibitors as potential drug candidates.
• Diagnostic Kits: A key component in the formulation of diagnostic kits for measuring enzyme activity in clinical and research laboratories.
• Biochemical Research: Used in fundamental biochemical studies to investigate enzyme mechanisms, specificity, and kinetics.
• Quality Control: Serves as a reference standard in the quality control of enzyme preparations and related biopharmaceutical products.

Basic Information

Product Name	Arg-Pro-p-Nitroanilide Acetate Salt
CAS No.	157054-08-5
Molecular Formula	C19H28N8O5 • C2H4O2
Molecular Weight	520.55 g/mol
Synonyms	H-Arg-Pro-pNA • Acetate; L-Arginyl-L-prolyl-4-nitroanilide acetate salt; Arg-Pro-4-NA Acetate; Bz-Arg-Pro-pNA Acetate (common variant); H-Arg-Pro-4-Nitroanilide Acetate; Protease Substrate pNA; Chromogenic Substrate for Trypsin; N-α-Benzoyl-L-arginyl-L-prolyl-4-nitroanilide acetate (related compound).
EINECS	Contact for details

Quality Control

Our Arg-Pro-p-Nitroanilide Acetate Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.