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(R)-1-Phenyl-2-Propanol CAS NO 157049-40-6


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CAS No.:157049-40-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-1-Phenyl-2-Propanol is a chiral secondary alcohol of significant importance in asymmetric synthesis and pharmaceutical manufacturing. This high-purity enantiomer serves as a versatile chiral building block and resolving agent for the production of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where stereochemical control is critical.

Application

  • Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
  • Asymmetric Synthesis & Catalysis: Used as a chiral auxiliary or ligand precursor in transition metal-catalyzed reactions to induce stereoselectivity.
  • Chiral Resolution Agent: Employed for the separation of racemic mixtures of acids or other compounds via diastereomeric salt formation.
  • Agrochemical Intermediate: Synthesis of enantiomerically pure pesticides and herbicides.
  • Flavor and Fragrance Industry: Production of chiral aroma chemicals where specific stereoisomers impart desired olfactory properties.
  • Academic and R&D Laboratories: Used in methodological development and research focused on stereochemistry and new synthetic pathways.

Basic Information

Product Name (R)-1-Phenyl-2-Propanol
CAS No. 157049-40-6
Molecular Formula C9H12O
Molecular Weight 136.19 g/mol
Synonyms (R)-(-)-1-Phenyl-2-propanol; (R)-1-Phenylpropan-2-ol; (R)-(-)-α-Methylbenzyl alcohol; (R)-(-)-α-Methylbenzenemethanol; (R)-Phenylmethylcarbinol; (R)-2-Hydroxy-1-phenylethane; (R)-Styryl alcohol; (R)-Benzenemethanol, α-methyl-, (αR)-
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Quality Control

Our (R)-1-Phenyl-2-Propanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC/HPLC) ≥ 98.0%
Enantiomeric Excess (ee) ≥ 99.0%
Specific Rotation [α] -40° to -44° (c=1 in ethanol)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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