Description

1,7,8-Indolizinetriol, Octahydro-6-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined indolizine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Natural Product Synthesis: Used as a core scaffold or intermediate in the total synthesis of complex indolizidine and related alkaloid natural products.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Medicinal Chemistry: Provides a versatile platform for structure-activity relationship (SAR) studies and library generation for high-throughput screening.
• Biochemical Research: May be utilized as a tool compound or inhibitor probe to study specific enzymatic or receptor-based biological processes.
• Fine Chemical Production: Acts as a high-value intermediate for the custom synthesis of specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	1,7,8-Indolizinetriol, Octahydro-6-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-71-9
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-6-methoxy-1,7,8-indolizinetriol; (1S,6R,7S,8R,8aR)-6-Methoxyoctahydro-1,7,8-indolizinetriol; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-6-methoxy-1,7,8-indolizinetriol; 6-Methoxy-octahydro-1,7,8-indolizinetriol (1S,6R,7S,8R,8aR)-; CAS 156205-71-9; Indolizinetriol derivative; Chiral indolizine scaffold.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1,7,8-Indolizinetriol, Octahydro-6-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is characterized and tested to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and residual solvents are available upon request. We adhere to cGMP principles for advanced pharmaceutical intermediates to ensure traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.