Description

Carbamic Acid, (1R,2R)-1,2-Cyclohexanediylbis-, Bis(1,1-Dimethylethyl) Ester, Rel- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant value in advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex molecules with precise three-dimensional architecture, a key requirement in modern pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly those targeting the central nervous system or requiring specific stereochemistry for efficacy.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysts, enabling enantioselective transformations.
• Agrochemical Research: Employed in the research and development of new, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Academic & Process Chemistry: Serves as a valuable reference standard and starting material in academic research and process optimization studies for route scouting and scale-up.
• Fine Chemical Synthesis: Utilized in the custom synthesis of complex, high-value specialty chemicals for various advanced material and electronic applications.

Basic Information

Product Name	Carbamic Acid, (1R,2R)-1,2-Cyclohexanediylbis-, Bis(1,1-Dimethylethyl) Ester, Rel- (9Ci)
CAS No.	155833-17-3
Molecular Formula	C16H28N2O4
Molecular Weight	312.41 g/mol
Synonyms	(1R,2R)-1,2-Cyclohexanediamine, N,N'-bis(1,1-dimethylethoxycarbonyl)-; (1R,2R)-N,N'-Di-Boc-1,2-diaminocyclohexane; (1R,2R)-N,N'-Di-tert-butoxycarbonyl-1,2-diaminocyclohexane; (R,R)-N,N'-Di-Boc-1,2-diaminocyclohexane; (R,R)-DACH Di-Boc; (1R,2R)-1,2-Bis[(tert-butoxycarbonyl)amino]cyclohexane; (1R,2R)-DACH-Boc2; rel-(1R,2R)-1,2-Cyclohexanediylbis-carbamic acid bis(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (1R,2R)-1,2-Cyclohexanediylbis-, Bis(1,1-Dimethylethyl) Ester, Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.