Description

Arachidonic Acid 1-(4,5-Dimethoxy-2-Nitrophenyl)Ethyl Ester is a specialized, photolabile derivative of arachidonic acid, a key polyunsaturated fatty acid involved in critical biological signaling pathways. This compound is engineered for advanced biochemical research, particularly in the study of lipid metabolism and cell signaling, where precise temporal and spatial control of arachidonic acid release is required. It is an essential tool for pharmaceutical R&D, academic laboratories, and biotechnology companies focused on inflammation, neurology, and cardiovascular research.

Application

• Photochemical Triggering in Cell Biology: Used as a "caged" arachidonic acid precursor in cellular assays to study the localized and timed release of arachidonic acid and its downstream metabolites (e.g., prostaglandins, leukotrienes) upon UV light exposure.
• Signal Transduction Research: A critical reagent for investigating the role of arachidonic acid in intracellular signaling cascades, receptor activation, and enzyme regulation (e.g., phospholipase A2, cyclooxygenase pathways).
• Neuroscience and Neuropharmacology: Applied in studies of synaptic plasticity, neurotransmitter release, and the effects of lipid mediators on neuronal function and survival.
• Inflammation and Immunology Studies: Facilitates research into the mechanisms of inflammatory responses, immune cell activation, and the development of novel anti-inflammatory therapeutics.
• Drug Discovery & High-Throughput Screening (HTS): Serves as a key component in assay development for screening compounds that modulate arachidonic acid pathways.
• Biochemical Tool Development: Used in the synthesis and development of novel probes and labeled derivatives for imaging and tracking lipid dynamics in live cells.

Basic Information

Product Name	Arachidonic Acid 1-(4,5-Dimethoxy-2-Nitrophenyl)Ethyl Ester
CAS No.	155613-96-0
Molecular Formula	C30H43NO6
Molecular Weight	513.67 g/mol
Synonyms	AA-DMNP Ester; Caged Arachidonic Acid; 1-(4,5-Dimethoxy-2-nitrophenyl)ethyl arachidonate; Arachidonic Acid, 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester; DMNP-caged Arachidonic Acid; (4,5-Dimethoxy-2-nitrophenyl)ethyl arachidonate; Photolabile Arachidonic Acid Ester
EINECS	Contact for details

Quality Control

Our Arachidonic Acid 1-(4,5-Dimethoxy-2-Nitrophenyl)Ethyl Ester is produced under strict quality management protocols to ensure the high purity and batch-to-batch consistency required for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	Yellow to orange viscous oil or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.