Description

3'-o-Galactopyranosylcytarabine is a glycosylated derivative of the nucleoside analog cytarabine, designed for targeted therapeutic delivery. This compound is significant for its potential to enhance drug solubility and modify pharmacokinetic profiles, offering a pathway to improved efficacy and reduced systemic toxicity. It is primarily of interest to pharmaceutical researchers and biotech developers working on advanced drug delivery systems, prodrug strategies, and novel oncology treatments.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of targeted anticancer prodrugs and novel therapeutic agents.
• Drug Delivery Research: Utilized in the development of glycosylated carrier systems to improve the bioavailability and tissue specificity of active pharmaceutical ingredients (APIs).
• Oncology R&D: Investigated for its role in creating more selective chemotherapeutic compounds that minimize off-target effects.
• Bioconjugation Studies: Acts as a model compound for studying carbohydrate-nucleoside linkages and their biological interactions.
• Biochemical Tool: Used in enzymatic studies and as a reference standard in analytical method development for nucleoside analogs.

Basic Information

Product Name	3'-o-Galactopyranosylcytarabine
CAS No.	155603-72-8
Molecular Formula	C19H27N3O10
Molecular Weight	457.43 g/mol
Synonyms	3'-O-β-D-Galactopyranosylcytarabine; Cytarabine 3'-O-β-D-galactopyranoside; 1-β-D-Arabinofuranosylcytosine 3'-O-β-D-galactopyranoside; Galactosylated Cytarabine; Ara-C 3'-Galactoside; 3'-O-(β-D-Galactopyranosyl)-1-β-D-arabinofuranosylcytosine
EINECS	Contact for details

Quality Control

Every batch of 3'-o-Galactopyranosylcytarabine is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to ensure it meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.