Description

(3α,5β,6α)-3,6-Dihydroxycholan-24-Oic Acid 4-(1-Oxopropyl)Phenyl Ester is a high-purity, synthetic bile acid derivative with significant value in advanced pharmaceutical research and development. This compound matters as a critical intermediate or reference standard for the synthesis of novel therapeutic agents targeting metabolic and liver-related pathways. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel bile acid analogs and steroidal drugs.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Metabolic Research: Employed in biochemical studies to investigate bile acid receptors (e.g., FXR, TGR5) and their role in cholesterol metabolism, glucose homeostasis, and inflammation.
• Drug Discovery: Acts as a precursor or pharmacophore for developing new therapeutic agents for liver diseases, cholestasis, and metabolic disorders.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research on sterol chemistry and biological pathway elucidation.

Basic Information

Product Name	(3α,5β,6α)-3,6-Dihydroxycholan-24-Oic Acid 4-(1-Oxopropyl)Phenyl Ester
CAS No.	155587-60-3
Molecular Formula	C33H48O6
Molecular Weight	540.74 g/mol
Synonyms	4-(1-Oxopropyl)phenyl 3α,6α-dihydroxy-5β-cholan-24-oate; Chenodeoxycholic Acid 4-Propiophenone Ester; 3α,6α-Dihydroxy-5β-cholan-24-oic Acid 4-Propiophenone Ester; CDC-Prop Ester; 155587-60-3; Bile Acid Derivative Ester; 4-Propiophenone Chenodeoxycholate
EINECS	Contact for details

Quality Control

Our (3α,5β,6α)-3,6-Dihydroxycholan-24-Oic Acid 4-(1-Oxopropyl)Phenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.