Description

1-Oleoyl-2-Cholesterylhemisuccinoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid derivative designed for advanced research and formulation applications. This compound is critical for creating stable, biomimetic lipid structures, offering researchers a reliable tool for studying membrane dynamics and developing targeted delivery systems. It is primarily utilized by scientists and product developers in the pharmaceutical, biotechnology, and advanced materials sectors for applications in drug delivery, diagnostic assays, and model membrane systems.

Application

• Liposome and Nanoparticle Formulation: A key component for constructing stable, long-circulating liposomes and lipid nanoparticles (LNPs) for drug and gene delivery.
• Biomimetic Membrane Research: Used to create advanced model membrane systems (e.g., supported lipid bilayers, vesicles) for studying protein-lipid interactions and membrane biophysics.
• Diagnostic Reagent Development: Serves as a functional coating or anchor point in diagnostic assays and biosensors to enhance specificity and signal detection.
• Targeted Drug Delivery Systems: Incorporated into lipid-based carriers to improve targeting efficiency and cellular uptake of therapeutic agents.
• Cryopreservation Media: Acts as a protective agent in specialized cryopreservation formulations for cells and sensitive biological materials.
• Cosmetic and Dermal Formulations: Used in high-end cosmetic products as a skin-identical lipid to improve barrier function and active ingredient delivery.

Basic Information

Product Name	1-Oleoyl-2-Cholesterylhemisuccinoyl-Sn-Glycero-3-Phosphocholine
CAS No.	155401-41-5
Molecular Formula	C73H134NO10P
Molecular Weight	1200.83 g/mol
Synonyms	Oleoyl-Cholesterylhemisuccinoyl Phosphatidylcholine; Cholesterol Hemisuccinate Oleoyl Phosphatidylcholine; O-CHEMS PC; 18:1 δ9-CHEMS PC; 1-Oleoyl-2-(cholesterylhemisuccinoyl)-sn-glycero-3-phosphocholine; CHEMS-Oleoyl PC; Asymmetric Phospholipid; Liposome-Forming Lipid E
EINECS	Contact for details

Quality Control

Every batch of 1-Oleoyl-2-Cholesterylhemisuccinoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for pharmaceutical research and in-vitro diagnostic use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to maintain stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.