Description

1-(4-(5-Maleimidopentyl)Aminobenzyl)Ethylenediaminetetraacetic Acid is a heterobifunctional crosslinking reagent that combines a maleimide group for thiol conjugation with a metal-chelating EDTA moiety. This compound matters for researchers and manufacturers requiring precise, site-specific bioconjugation while maintaining the ability to chelate metal ions for purification, detection, or therapeutic purposes. It is primarily needed by professionals in bioconjugation, diagnostic assay development, and targeted drug delivery systems, where stable protein-antibody linkages and metal handling are critical.

Application

• Site-specific protein labeling and modification via thiol-maleimide chemistry.
• Preparation of chelator-conjugated antibodies for radioimmunoassays (RIA) and radioimmunotherapy.
• Development of bifunctional probes for molecular imaging, particularly in conjunction with radionuclides.
• Immobilization of thiol-containing biomolecules onto solid supports functionalized with metal ions.
• Conjugation in ADC (Antibody-Drug Conjugate) linker-payload chemistry research.
• Surface functionalization of nanoparticles for targeted delivery and diagnostics.
• As a specialized reagent in biomaterial and biosensor fabrication.

Basic Information

Product Name	1-(4-(5-Maleimidopentyl)Aminobenzyl)Ethylenediaminetetraacetic Acid
CAS No.	155015-71-7
Molecular Formula	C28H39N5O10
Molecular Weight	605.64 g/mol
Synonyms	Maleimide-PEG5-amine-EDTA; 1-(4-((5-Maleimidopentyl)amino)benzyl)EDTA; EDTA-Maleimide crosslinker; Maleimido-C5-EDTA; p-SCN-Bn-EDTA Maleimide derivative; Heterobifunctional EDTA-Maleimide linker; N-(5-Maleimidopentyl)-4-(EDTA-methyl)aniline; Bifunctional Chelator with Maleimide
EINECS	Contact for details

Quality Control

Our 1-(4-(5-Maleimidopentyl)Aminobenzyl)Ethylenediaminetetraacetic Acid is produced under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant cGMP and ISO 9001 standards for critical raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.