Description

1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pc is a specialized, high-purity phospholipid derivative, a key intermediate in lipid biochemistry and pharmaceutical research. This compound is crucial for studying the role of oxidized phospholipids in cellular signaling pathways, inflammation, and oxidative stress responses. It is primarily utilized by research institutions, pharmaceutical developers, and advanced diagnostic companies focused on lipidomics, drug discovery, and the development of targeted therapies.

Application

• Biochemical Research: As a critical standard and substrate for investigating phospholipase A2 (PLA2) activity and the metabolism of oxidized phospholipids.
• Lipidomics & Metabolomics: Used as a reference compound in mass spectrometry-based profiling to identify and quantify oxidized lipid species in biological samples.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel drug candidates targeting inflammatory pathways and oxidative damage.
• Cell Signaling Studies: Employed to elucidate the mechanisms of action of oxidized phospholipids in cell membrane dynamics and signal transduction.
• Diagnostic Reagent Manufacturing: A potential component in the development of high-sensitivity assay kits for detecting biomarkers of oxidative stress.
• Academic Research: Fundamental tool for universities and research labs studying atherosclerosis, neurodegenerative diseases, and other conditions linked to lipid peroxidation.

Basic Information

Product Name	1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pc
CAS No.	154436-48-3
Molecular Formula	C46H84NO10P
Molecular Weight	842.14 g/mol
Synonyms	1-Stearoyl-2-(15S-hydroperoxyeicosatetraenoyl)-sn-glycero-3-phosphocholine; 15(S)-HPETE-PC; Oxidized Phosphatidylcholine; PLPC 15(S)-HPETE; 1-Octadecanoyl-2-[15(S)-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl]-sn-glycero-3-phosphocholine; 15S-HpETE-PC; 1-Stearoyl-2-15(S)-Hpete-GPC
EINECS	Contact for details

Quality Control

Every batch of 1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pc is produced and analyzed under strict quality management protocols to ensure identity, purity, and stability. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, LC-MS) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95%
15(S)-HPETE Isomer Purity	≥ 90% of total HPETE isomers
Solubility	Soluble in chloroform, ethanol; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.