Description

Sq-Nhs* CAS NO 154161-81-6 is a specialized, high-purity chemical intermediate widely utilized in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for researchers and production chemists in the pharmaceutical, agrochemical, and biotechnology industries who require reliable, high-quality intermediates for coupling and conjugation reactions.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Bioconjugation: Used for labeling and crosslinking biomolecules such as proteins, peptides, and antibodies in diagnostic and therapeutic applications.
• Peptide Synthesis: Serves as an activating agent for carboxylic acids in solid-phase and solution-phase peptide synthesis.
• Polymer Chemistry: Employed in the modification and functionalization of polymers to introduce specific reactive groups.
• Material Science: Facilitates surface modification and the creation of functionalized materials for sensors and advanced coatings.
• Research & Development: A versatile tool in academic and industrial R&D labs for exploring new synthetic pathways and creating molecular probes.

Basic Information

Product Name	Sq-Nhs*
CAS No.	154161-81-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Hydroxysuccinimide ester derivative; Succinimidyl ester; NHS ester; Active ester; Sq-NHS ester; 154161-81-6; 2,5-Dioxopyrrolidin-1-yl ester
EINECS	Contact for details

Quality Control

Our Sq-Nhs* is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.