Description

2′-Phosphoadenosine 5′-Phosphate Sodium Salt is a high-purity biochemical reagent and a key phosphorylated derivative of adenosine. This compound serves as a critical co-substrate and intermediate in numerous enzymatic reactions, particularly those involving sulfuryltransferases and phosphotransferases. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science research sectors, where it is used in enzyme studies, metabolic pathway analysis, and the synthesis of nucleotide-based therapeutics.

Application

• Enzymology Research: Used as a co-substrate for studying sulfotransferase and kinase enzyme kinetics and mechanisms.
• Metabolic Pathway Analysis: A vital intermediate in the study of sulfur metabolism and adenosine 3',5'-bisphosphate (PAP) related pathways.
• Pharmaceutical Development: Employed in the research and production of nucleotide-based drugs and prodrugs.
• Biochemical Assays: Serves as a standard or critical reagent in high-throughput screening (HTS) and diagnostic assay development.
• Cell Signaling Studies: Utilized to investigate intracellular signaling pathways that involve nucleotide phosphorylation.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method validation in QC laboratories.

Basic Information

Product Name	2′-Phosphoadenosine 5′-Phosphate Sodium Salt
CAS No.	154146-84-6
Molecular Formula	C10H12N5Na2O12P2 • xH2O
Molecular Weight	Anhydrous: 493.15 g/mol
Synonyms	PAPS, Sodium Salt; Adenosine 3',5'-bisphosphate, sodium salt; 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) sodium salt (common alias); 2'-Phosphoadenylyl sulfate sodium salt; Adenosine 2'-phosphate 5'-phosphosulfate; PAPS-Na2; 3'-Phosphoadenosine 5'-phosphosulfate sodium salt; 2'-PAPS Na
EINECS	Contact for details

Quality Control

Our 2′-Phosphoadenosine 5′-Phosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.