Description

Brinzolamide CAS NO 154127-19-2 is a potent and selective carbonic anhydrase inhibitor used primarily as an active pharmaceutical ingredient (API). This compound is critical for the formulation of ophthalmic solutions designed to lower elevated intraocular pressure. It is essential for pharmaceutical manufacturers and R&D facilities developing treatments for conditions such as open-angle glaucoma and ocular hypertension.

Application

• Primary Active Pharmaceutical Ingredient (API) in ophthalmic solutions for glaucoma.
• Key component in the formulation of ophthalmic suspensions and eye drops.
• Research and development of novel carbonic anhydrase inhibitor-based therapies.
• Manufacturing of generic and branded anti-glaucoma medications.
• Use in preclinical and clinical studies for ocular drug delivery systems.
• Reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Brinzolamide
CAS No.	154127-19-2
Molecular Formula	C12H21N3O5S3
Molecular Weight	383.51 g/mol
Synonyms	(4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide; AL-4862; Azopt; Brinzolamide; 1,1-Dioxo-N-[(4S,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]-N-ethyl-λ⁶-thiophene-2-sulfonamide
EINECS	Contact for details

Quality Control

Our Brinzolamide is manufactured under strict quality systems and undergoes rigorous testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Each batch is tested against relevant pharmacopeial specifications (e.g., USP, EP) for identity, purity, and potency. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.