Description

3-α-Chloro-Imperialine is a high-purity, semi-synthetic alkaloid derivative of imperialine, a compound of significant interest in pharmaceutical research. This chlorinated analog is valued for its potential as a key intermediate in the development of novel bioactive molecules and therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced organic synthesis, medicinal chemistry, and the exploration of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroidal alkaloid derivatives for pharmacological evaluation.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with potential therapeutic applications.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in laboratories.
• Academic & Industrial R&D: Employed in organic synthesis projects within university and corporate research and development departments.
• Biochemical Research: Investigated for its interaction with biological targets and potential biological activity.

Basic Information

Product Name	3-α-Chloro-Imperialine
CAS No.	153720-48-0
Molecular Formula	C27H42ClNO2
Molecular Weight	448.08 g/mol
Synonyms	3α-Chloroimperialine; Imperialine, 3-chloro-; 3-Chloroimperialine; (3α,5β,17β,20α)-3-Chlorocevan-6-one, 20-hydroxy-; 3-Chloro-20-hydroxycevan-6-one; 3-Chloro-17,23-epoxy-3,14-dihydroxycevan-6-one (related structure); Imperialine chlorohydrin derivative
EINECS	Contact for details

Quality Control

Our 3-α-Chloro-Imperialine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.