Description

9-Nitro Minocycline Sulfate Salt is a chemically modified derivative of the broad-spectrum tetracycline antibiotic, minocycline. This nitrated analog is a critical pharmaceutical intermediate and research chemical used in the development of novel therapeutic agents and for advanced biochemical studies. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and academic institutions focused on antimicrobial and anti-inflammatory research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of next-generation tetracycline-class antibiotics and other bioactive molecules.
• Biochemical Research: Used as a reference standard and probe compound in studies investigating bacterial resistance mechanisms and protein synthesis inhibition.
• Anti-inflammatory Research: Investigated in preclinical models for its potential modulatory effects on inflammatory pathways beyond its antimicrobial activity.
• Academic & Discovery Chemistry: Serves as a starting material for medicinal chemistry programs aiming to improve drug potency, reduce side effects, or overcome resistance.
• Analytical Standard: Employed for method development, calibration, and quality control in HPLC and LC-MS analysis within pharmaceutical quality assurance labs.

Basic Information

Product Name	9-Nitro Minocycline Sulfate Salt
CAS No.	153621-80-8
Molecular Formula	C₂₃H₂₇N₅O₈ • xH₂SO₄
Molecular Weight	Contact for details
Synonyms	9-Nitro Minocycline Sulfate
Minocycline, 9-nitro-, sulfate salt
9-Nitro Minocycline Sulphate
9-Nitro-7-dimethylamino-6-demethyl-6-deoxytetracycline sulfate
9-Nitro MINO sulfate
CAS 153621-80-8
Nitrated Minocycline Sulfate
EINECS	Contact for details

Quality Control

Every batch of 9-Nitro Minocycline Sulfate Salt is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and development needs. A Certificate of Analysis (COA) detailing purity (by HPLC), water content, and identification tests is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.