Description

H-Thr-Glu-Pro-Glu-Tyr(Po3H2)-Gln-Pro-Gly-Glu-Nh2 is a chemically synthesized, phosphorylated peptide sequence. This compound is a critical research-grade biochemical used as a specific substrate or inhibitor in enzymatic studies, particularly for investigating kinase and phosphatase activity. It is essential for pharmaceutical R&D, academic research, and diagnostic development focused on signal transduction pathways and protein-protein interactions.

Application

• Biochemical Research: Used as a specific substrate for studying protein kinase and phosphatase enzyme kinetics and mechanisms.
• Pharmaceutical Development: Serves as a key tool compound in drug discovery programs targeting phosphorylation-dependent diseases.
• Diagnostic Assay Development: Employed in the development of ELISA and other immunoassays to detect phospho-specific antibodies or enzyme activity.
• Cell Signaling Studies: Applied in cellular assays to modulate or monitor specific phosphorylation events within signal transduction cascades.
• Peptide Library Synthesis: Acts as a building block or a reference standard in the synthesis of focused peptide libraries for high-throughput screening.

Basic Information

Product Name	H-Thr-Glu-Pro-Glu-Tyr(Po3H2)-Gln-Pro-Gly-Glu-Nh2
CAS No.	153586-97-1
Molecular Formula	C50H71N11O25P
Molecular Weight	1260.13 g/mol
Synonyms	Phosphorylated Peptide TEPEYQPG; pTyr-TEPEYQPG; H-Thr-Glu-Pro-Glu-pTyr-Gln-Pro-Gly-Glu-NH2; TEPE(pY)QPG; Phosphotyrosine-containing peptide; EGFR-derived phosphopeptide (1042-1050); pY1068 peptide analog; Research peptide 153586-97-1
EINECS	Contact for details

Quality Control

Our research-grade peptides are manufactured under strict quality systems. Each batch of H-Thr-Glu-Pro-Glu-Tyr(Po3H2)-Gln-Pro-Gly-Glu-Nh2 undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, ensuring reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.