Description

Uridine 5'-Diphospho-Galactose-[Galactose-6-3H] Ammonium Salt is a high-specific-activity, tritium-labeled nucleotide sugar essential for studying galactose metabolism and glycosylation pathways. This compound serves as a critical radiolabeled tracer for precise, quantitative analysis in biochemical and enzymatic research. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic sectors for investigating enzyme kinetics, substrate specificity, and metabolic flux.

Application

• Enzymatic Assay Substrate: Used as a radiolabeled co-substrate for assays involving galactosyltransferases, such as β-1,4-galactosyltransferase, to study glycosylation mechanisms.
• Metabolic Pathway Tracing: Enables the tracing and quantification of galactose incorporation into glycoproteins, glycolipids, and proteoglycans in cell-based and in vitro systems.
• Drug Discovery & Development: Supports high-throughput screening (HTS) and characterization of inhibitors targeting glycosyltransferase enzymes for therapeutic intervention.
• Diagnostic Reagent Manufacturing: Employed in the development and calibration of diagnostic kits for disorders of galactose metabolism (e.g., galactosemia).
• Biochemical Research: Fundamental tool for studying the biosynthesis of cell surface antigens, blood group substances, and other glycoconjugates.
• Quality Control (QC): Serves as a reference standard in QC laboratories to validate analytical methods for nucleotide sugars and related metabolites.

Basic Information

Item	Detail
Product Name	Uridine 5'-Diphospho-Galactose-[Galactose-6-3H] Ammonium Salt
CAS No.	152585-43-8
Molecular Formula	C15H27N3O17P2 * 3H * xNH3
Molecular Weight	Approx. 607.3 (unlabeled ammonium salt) + 3H
Synonyms	UDP-[6-3H]Galactose; UDP-Galactose, [galactose-6-3H]-; Tritiated UDP-Galactose; UDP-[6-3H]Gal; Uridine diphosphogalactose (tritiated); Ammonium UDP-[3H]Galactose; 5'-UDP-Galactose, [6-3H]-; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with [6-3H]-D-galactose, ammonium salt
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled biochemicals is produced and tested under stringent conditions to ensure high radiochemical purity and specific activity, which are critical for sensitive research applications. Quality is verified via analytical techniques including HPLC with radiometric detection. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, solvent composition, and analytical chromatograms is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at or below -20°C. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or frozen solution
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	15-40 Ci/mmol (Contact for exact value)
Chemical Purity (HPLC, UV)	≥ 90%
Solvent	Ethanol:Water mixture or as specified
Concentration	1 mCi/mL (Nominal)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.