Description

Abz-Gln-Val-Val-Ala-Gly-Ala-Ethylenediamine-Dnp CAS NO 152390-52-8 is a specialized, high-purity synthetic peptide derivative designed for advanced biochemical research and development. This compound is critical for researchers investigating protease activity, enzyme kinetics, and the development of novel diagnostic assays and therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on proteomics and drug discovery.

Application

• Protease Substrate & Enzyme Assay Development: Serves as a specific, fluorogenic substrate for studying the activity and inhibition of target proteases.
• Biochemical Research: Used in kinetic studies to determine enzyme constants (Km, Vmax) and elucidate proteolytic pathways.
• Pharmaceutical Screening: Integral to high-throughput screening (HTS) platforms for identifying and characterizing new protease inhibitor drug candidates.
• Diagnostic Reagent Formulation: A key component in the development of sensitive and specific clinical diagnostic kits for detecting protease-related diseases.
• Cell Biology & Signal Transduction Studies: Employed to monitor and manipulate specific proteolytic events within cellular systems.

Basic Information

Product Name	Abz-Gln-Val-Val-Ala-Gly-Ala-Ethylenediamine-Dnp
CAS No.	152390-52-8
Molecular Formula	C46H66N14O15
Molecular Weight	1031.1 g/mol
Synonyms	Abz-QVVAGY-EDDnp; Abz-Gln-Val-Val-Ala-Gly-Tyr-EDDnp; (2,4-Dinitrophenyl)ethylenediamine-Abz-Gln-Val-Val-Ala-Gly-Tyr; Fluorogenic Peptide Substrate Abz-QVVAGY-EDDnp; FRET Peptide Substrate; Protease Substrate 152390-52-8; Peptide for Cathepsin/Cathepsin-like protease studies
EINECS	Contact for details

Quality Control

Our Abz-Gln-Val-Val-Ala-Gly-Ala-Ethylenediamine-Dnp is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity verification and MS for identity confirmation. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.