Description

6-Demethyl-9-(N,n-Dimethylglycylamido)-6-Deoxytetracycline is a chemically modified tetracycline derivative, representing a significant advancement in the development of novel semi-synthetic antibiotics. This compound is engineered to address challenges related to bacterial resistance and to enhance pharmacological properties. It is primarily utilized in advanced pharmaceutical research and development for creating next-generation antimicrobial agents, as well as in biochemical studies investigating protein synthesis inhibition.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel tetracycline-class antibiotics with improved efficacy and spectrum of activity.
• Antimicrobial Research: Used as a reference standard and active compound in microbiological and biochemical research to study mechanisms of action against resistant bacterial strains.
• Veterinary Medicine Development: Investigated for the formulation of new therapeutic agents for bacterial infections in animals.
• Biochemical Tool Compound: Employed in laboratory studies to probe ribosomal function and protein synthesis pathways.
• API Synthesis: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting complex infections.

Basic Information

Product Name	6-Demethyl-9-(N,n-Dimethylglycylamido)-6-Deoxytetracycline
CAS No.	151922-17-7
Molecular Formula	C₂₇H₃₃N₃O₈
Molecular Weight	527.57 g/mol
Synonyms	9-(N,N-Dimethylglycylamido)-6-demethyl-6-deoxytetracycline; 6-Demethyl-9-(N,N-dimethylglycylamido)-6-deoxytetracycline; Tigecycline Impurity; Tygacil Related Compound; (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-9-[(2-(dimethylamino)acetyl]amino]-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Demethyl-9-(N,n-Dimethylglycylamido)-6-Deoxytetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.