Description

9-(N,n-Dimethylglycylamido)Minocycline is a chemically modified derivative of the broad-spectrum tetracycline antibiotic, minocycline. This semi-synthetic compound is engineered to enhance specific pharmacological properties, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of anti-infectives and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel tetracycline-class antibiotics with potentially improved efficacy or reduced side effects.
• Biomedical Research: Used as a reference standard or active compound in biochemical and microbiological assays to study bacterial resistance mechanisms.
• Drug Discovery Programs: Employed in medicinal chemistry for structure-activity relationship (SAR) studies to develop next-generation anti-infective therapies.
• API Development: Acts as a precursor in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) targeting complex infections.

Basic Information

Product Name	9-(N,n-Dimethylglycylamido)Minocycline
CAS No.	151922-16-6
Molecular Formula	C₂₈H₃₈N₆O₈
Molecular Weight	586.64 g/mol
Synonyms	9-(N,N-Dimethylglycylamido)minocycline; Minocycline 9-(N,N-dimethylglycyl) derivative; DMG-Minocycline; (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-9-[[2-(dimethylamino)acetyl]amino]-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; Glycylminocycline derivative; N,N-Dimethylglycylminocycline
EINECS	Contact for details

Quality Control

Our 9-(N,n-Dimethylglycylamido)Minocycline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.