Description

8-Aminoadenosine Cyclic 3',5'-(Hydrogen Phosphate) 5'-Ribofuranosyl Ester is a chemically modified nucleoside analog, specifically a derivative of adenosine 3',5'-cyclic monophosphate (cAMP). This compound is of significant interest in biochemical and pharmacological research due to its role as a potential modulator of cyclic nucleotide-dependent signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of cell signaling, enzyme kinetics, and the development of novel therapeutic agents targeting PKA and other cAMP-responsive elements.

Application

• Biochemical Research: Used as a key reagent and reference standard in studies of cyclic nucleotide signaling cascades and protein kinase A (PKA) activation.
• Pharmaceutical R&D: Serves as a crucial intermediate or lead compound in the discovery and development of drugs targeting cardiovascular diseases, metabolic disorders, and neurological conditions.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the specificity and mechanism of phosphodiesterases (PDEs) and adenylate cyclases.
• Cell Signaling Probes: Utilized in cellular assays to modulate intracellular cAMP levels and study downstream effects on gene expression and cell function.
• Academic Research: Fundamental tool for universities and research labs exploring the structural biology of nucleotide-binding sites and receptor interactions.

Basic Information

Product Name	8-Aminoadenosine Cyclic 3',5'-(Hydrogen Phosphate) 5'-Ribofuranosyl Ester
CAS No.	151898-25-8
Molecular Formula	C15H18N7O7P
Molecular Weight	439.32 g/mol
Synonyms	8-Aminoadenosine 3',5'-cyclic monophosphate; 8-NH2-cAMP; 8-Amino-cAMP; 8-Aminoadenosine 3',5'-cyclic phosphate; 8-Amino-cyclic AMP; 8-Amino-adenosine cyclic 3',5'-monophosphate; 8-Amino-3',5'-cAMP; 8-Aminoadenosine 3',5'-cyclic phosphate 5'-ribofuranosyl ester
EINECS	Contact for details

Quality Control

Our 8-Aminoadenosine Cyclic 3',5'-(Hydrogen Phosphate) 5'-Ribofuranosyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All materials undergo comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.