Description

Sapacitabine CAS NO 151823-14-2 is a synthetic nucleoside analog with significant potential in pharmaceutical research and development. This compound is primarily valued for its role as a cytarabine prodrug, designed to improve therapeutic efficacy and bioavailability in targeted treatments. It is of critical interest to researchers and manufacturers in the oncology and antiviral drug development sectors. Our supply ensures high purity and batch-to-batch consistency for reliable experimental and formulation work.

Application

• Oncology Research: As a prodrug of cytarabine, it is a key investigational compound in the development of novel chemotherapeutic agents for leukemia and other cancers.
• Antiviral Drug Development: Explored for its potential activity against viral infections due to its nucleoside analog structure.
• Biochemical Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in pharmacokinetic and metabolic studies.
• Pharmaceutical Formulation: Serves as a critical starting material or intermediate in the synthesis of more complex therapeutic molecules.
• Mechanism of Action Studies: Employed in cellular and molecular biology research to study DNA synthesis inhibition and cell cycle arrest.
• Preclinical Development: Essential for in vitro and in vivo testing during the drug discovery pipeline.

Basic Information

Product Name	Sapacitabine
CAS No.	151823-14-2
Molecular Formula	C15H19FN4O5
Molecular Weight	362.34 g/mol
Synonyms	CS-682; CYC-682; 4'-Thio-2'-deoxy-2',2'-difluorocytidine; 1-(4-Thio-2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)cytosine; 2'-Deoxy-2',2'-difluoro-4'-thiocytidine; 4'-Thioarabinofuranosyl-2'-deoxy-2',2'-difluorocytidine
EINECS	Contact for details

Quality Control

Our Sapacitabine is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical research. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.