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N,n-Dimethylsphingosine-1-Phosphate CAS NO 151729-53-2


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CAS No.:151729-53-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,n-Dimethylsphingosine-1-Phosphate is a chemically modified sphingolipid metabolite that serves as a potent and selective modulator of sphingosine-1-phosphate (S1P) receptor signaling pathways. This compound is of significant value in biochemical and pharmacological research for investigating cellular processes such as proliferation, migration, and immune cell trafficking. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and advanced cell signaling studies.

Application

  • Biochemical Research: Used as a high-purity reference standard and tool compound for studying S1P receptor biology and sphingolipid metabolism.
  • Drug Discovery & Development: Serves as a key intermediate or pharmacological probe in the development of novel therapeutics targeting immune disorders, inflammation, and cancer.
  • Cell Signaling Studies: Employed in vitro and in cell-based assays to elucidate the role of S1P pathways in angiogenesis, vascular integrity, and lymphocyte egress.
  • Academic Research: Utilized in university and institutional labs for fundamental research into lipid-mediated signal transduction.
  • Pharmaceutical Intermediates: Acts as a critical synthetic building block for the preparation of more complex S1P receptor agonists or antagonists.

Basic Information

Product Name N,n-Dimethylsphingosine-1-Phosphate
CAS No. 151729-53-2
Molecular Formula C20H42NO5P
Molecular Weight 407.53 g/mol
Synonyms DMS1P; N,N-Dimethylsphingosine 1-Phosphate; N,N-Dimethyl-D-erythro-sphingosine 1-phosphate; (2S,3R,4E)-2-(Dimethylamino)-3-hydroxy-4-octadecen-1-yl dihydrogen phosphate; Dimethylsphingosine phosphate; S1P Receptor Modulator; 151729-53-2
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Quality Control

Our N,n-Dimethylsphingosine-1-Phosphate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMSO, ethanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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