Description

Hemoglobin Karlskoga is a specific, well-characterized variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for advanced research and development in life sciences, where precise molecular behavior is paramount. It serves as a vital reference standard and raw material for researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors, particularly in studies of hemoglobinopathies, oxygen therapeutics, and biosensor development.

Application

• Biochemical Research & Development: Used as a purified reference standard in studies of protein structure, function, and ligand-binding kinetics.
• Diagnostic Reagent Manufacturing: Serves as a key component in the calibration and production of in-vitro diagnostic (IVD) kits for blood gas analysis and hematology.
• Pharmaceutical Development: Investigated as a potential starting material or model compound in the research of blood substitutes and oxygen-carrying therapeutics.
• Academic & Clinical Studies: Employed in university and hospital laboratories for fundamental research into sickle cell disease, thalassemia, and other hemoglobin-related disorders.
• Biosensor Technology: Utilized in the development of enzymatic and optical biosensors due to its intrinsic redox and oxygen-binding properties.
• Quality Control Standards: Acts as a control material in analytical laboratories to ensure the accuracy of hemoglobin testing methods.

Basic Information

Product Name	Hemoglobin Karlskoga
CAS No.	151248-26-9
Molecular Formula	C2952H4664N812O840S8Fe4
Molecular Weight	~64.5 kDa (Tetramer)
Synonyms	Hb Karlskoga; Hemoglobin variant Karlskoga; α-2 globin chain variant; HBA2 Karlskoga; Deoxyhemoglobin Karlskoga; Oxyhemoglobin Karlskoga; Methemoglobin Karlskoga; Human Hemoglobin Karlskoga
EINECS	Contact for details

Quality Control

Our Hemoglobin Karlskoga is produced and handled under stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including purity assay, spectral analysis, and electrophoretic characterization, to ensure identity, strength, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake. Aliquot contents to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (UV-Vis)	Conforms to standard spectrum
Purity (HPLC)	≥ 95% (Hemoglobin Karlskoga)
Protein Content (Biuret)	≥ 90%
Methemoglobin Content	≤ 5%
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg (for applicable grades)
Biological Activity (O2 binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.