Description

Nir-667 n-Succinimidyl Ester is a high-purity, reactive chemical intermediate designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring reliable, site-specific modification of biomolecules, such as proteins and antibodies, with near-infrared (NIR) fluorescent probes. It is essential for professionals in pharmaceutical R&D, diagnostic assay development, and life science research who need precise and stable fluorescent labeling for imaging, detection, and analysis.

Application

• Bioconjugation Reagent: Primary use for covalent attachment of Nir-667 fluorophore to amines on proteins, peptides, and antibodies.
• Fluorescent Probe Synthesis: Key intermediate in the preparation of active NIR dyes for in vitro and in vivo imaging.
• Diagnostic Assay Development: Used to label detection antibodies or antigens in ELISA, lateral flow assays, and other immunoassays.
• Biomedical Research: Enables labeling of cellular components for fluorescence microscopy, flow cytometry, and small animal imaging studies.
• Pharmaceutical Analysis: Utilized in the development of drug-antibody conjugates (DACs) or for tracking drug distribution.
• Material Science: Functionalization of nanoparticles or polymers with NIR fluorescent tags for sensor applications.

Basic Information

Product Name	Nir-667 n-Succinimidyl Ester
CAS No.	151134-79-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NIR-667 NHS Ester; Nir667 Succinimidyl Ester; Nir 667 SE; Nir667-NHS; NSC 151134-79-1; Nir-667, N-succinimidyl ester; Nir667 Fluorescent Dye NHS Ester; Near-Infrared 667 NHS Ester
EINECS	Contact for details

Quality Control

Our Nir-667 n-Succinimidyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic identification (NMR, MS). Certificates of Analysis (COA) with detailed specifications are provided to guarantee the product meets the stringent requirements for sensitive bioconjugation work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.