Description

2-Amino-1-[5-o-[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-4(1H)-Pyrimidinone is a high-purity, phosphorylated nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. Its complex structure, featuring multiple phosphate groups, makes it a critical building block for synthesizing novel nucleotide analogs and probes. This compound is essential for researchers and manufacturers in nucleic acid chemistry, antiviral drug discovery, and molecular biology, where precise chemical modifications are required to study or modulate biological pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly those involving kinases and polymerases.
• Probe Development: Serves as a building block for creating labeled nucleotides used in diagnostic assays and imaging techniques.
• Nucleic Acid Chemistry: Employed in the synthesis of modified oligonucleotides with tailored properties for therapeutic or diagnostic applications.
• Enzyme Mechanism Studies: Utilized to investigate the structure and function of enzymes that interact with phosphorylated nucleotides.

Basic Information

Product Name	2-Amino-1-[5-o-[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-4(1H)-Pyrimidinone
CAS No.	150668-55-6
Molecular Formula	C9H16N3O14P3
Molecular Weight	507.15 g/mol
Synonyms	2-Amino-9-(5-O-{[Hydroxy(phosphonooxy)phosphoryl]oxy}phosphono-β-D-ribofuranosyl)-1,9-dihydro-4H-purin-4-one; 2-Amino-IMP triphosphate; 2-Amino-inosine triphosphate; 2-Amino-ITP; 2-Amino-1-(5-O-{hydroxy[hydroxy(phosphonooxy)phosphoryl]oxy}phosphono-β-D-ribofuranosyl)-1,4-dihydropyrimidin-4-one; 2-Aminopurine riboside triphosphate analog; Nucleotide analog CAS 150668-55-6
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-1-[5-o-[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]-β-D-Ribofuranosyl]-4(1H)-Pyrimidinone is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may lead to decomposition. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.